OBO ID: CHEBI:92369

Term Name:	SU4312		Search Ontology:
Synonyms:	3-(4-dimethylamino-benzylidenyl)-2-indolinone 3-[4-(dimethylamino)benzylidene]-1,3-dihydro-2H-indol-2-one 3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one DMBI SU 4312 SU-4312
Definition:	A member of the class of oxindoles that is 3-methyleneoxindole in which one of the hydrogens of the methylene group has been replaced by a p-(dimethylamino)phenyl group. SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein tyrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor. It also inhibits the neuronal nitric oxide synthase (NOS) and exhibits neuroprotection against NO-mediated neurotoxicity.
References:	CAS:5812-07-7 LINCS:LSM-2454 PMID:19235725 PMID:23062100 PMID:24134630 PMID:26327470 PMID:26820057 PMID:28807675 Reaxys:28935825
Ontology:	ChEBI  ( EBI )