OBO ID: CHEBI:78332
Term Name: Src Inhibitor-1 Search Ontology:
Synonyms:
  • (4'-oxyphenyl-phenylamino)-6,7-dimethoxyquinazoline
  • 4-(4'-phenoxyanilino)-6,7-dimethoxyquinazoline
  • 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine
  • 6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine
  • SKI-1
  • Src kinase inhibitor I
  • Src-l1
Definition: A member of the class of quinazolines that is quinazoline which is substituted at position 4 by a p-phenoxyanilino group and at positions 6 and 7 by methoxy groups. It is a potent, competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor. Src Inhibitor-1 is one of the 'gold standards' for Src kinase inhibition that has been shown to use PP1 or PP2 in parallel with Src-I1 to inhbit Src family kinases.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available