OBO ID: CHEBI:76612
Term Name: ibrutinib Search Ontology:
Synonyms:
  • 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one
  • ibrutinib
  • ibrutinibum
  • IMBRUVICA
  • PCI 32765
  • PCI-32765
  • PCI32765
Definition: A member of the class of acrylamides that is (3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine in which the piperidine nitrogen is replaced by an acryloyl group. A selective and covalent inhibitor of the enzyme Bruton's tyrosine kinase, it is used for treatment of B-cell malignancies.
References:
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available