Term Name: |
esmolol |
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Search Ontology:
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Synonyms: |
- (+-)-esmolol
- (+-)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate
- 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester
- esmolol
- esmololum
- Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate
- methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate
- rac-methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate
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Definition: |
A racemate comprising equimolar amounts of (R)- and (S)-esmolol. A cardioselective and short-acting beta1 receptor blocker with rapid onset but lacking intrinsic sympathomimetic and membrane-stabilising properties, it is used as the hydrochloride salt in the management of supraventricular arrhythmias, and for the control of hypertension and tachycardia during surgery. While the S enantiomer possesses all of the heart rate control, both enantiomers contribute to lowering blood pressure.
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References: |
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Ontology: |
ChEBI
(
EBI
)
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