ZFIN ChEBI: 3,3',5-triiodo-L-thyronine

OBO ID: CHEBI:18258

Term Name:	3,3',5-triiodo-L-thyronine		Search Ontology:
Synonyms:	3,3',5-triiodo-L-thyronine 3,5,3'-Triiodo-L-thyronine 3,5,3'-Triiodothyronine 3,5,3'TRIIODOTHYRONINE 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine L-3,5,3'-Triiodothyronine L-T3 Liothyronine liothyroninum liotironina O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine T3 Tertroxin Tresitope Triiodothyronine
Definition:	An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
References:	Beilstein:2710227 CAS:6893-02-3 DrugBank:DB00279 Drug_Central:1585 HMDB:HMDB0000265 KEGG:C02465 KEGG:D08128 LINCS:LSM-3991 MetaCyc:CPD-10813 PDBeChem:T3 PMID:11738632 PMID:15206581 PMID:19339791 Reaxys:2710227 Wikipedia:Triiodothyronine
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	2-halophenol iodophenol iodothyronine 2-halophenol iodophenol iodothyronine Show first 5 Terms
has_role:	human metabolite mouse metabolite thyroid hormone human metabolite mouse metabolite thyroid hormone Show first 5 Terms
inverse has_functional_parent:	3,3',5-triiodo-L-thyronine sulfate 3,3',5-triiodo-L-thyronine sulfate Show first 5 Terms
inverse has_part:	desiccated thyroid extract desiccated thyroid extract Show first 5 Terms
inverse is_conjugate_base_of:	3,3',5-triiodo-L-thyroninate 3,3',5-triiodo-L-thyroninate Show first 5 Terms
inverse is_substituent_group_from:	3,3',5-triiodo-L-thyronine residue 3,3',5-triiodo-L-thyronine residue Show first 5 Terms
inverse is_tautomer_of:	3,3',5-triiodo-L-thyronine zwitterion 3,3',5-triiodo-L-thyronine zwitterion Show first 5 Terms
is_conjugate_acid_of:	3,3',5-triiodo-L-thyroninate 3,3',5-triiodo-L-thyroninate Show first 5 Terms
is_tautomer_of:	3,3',5-triiodo-L-thyronine zwitterion 3,3',5-triiodo-L-thyronine zwitterion Show first 5 Terms

PHENOTYPE No data available