ZFIN ChEBI: JTE-607 free base

OBO ID: CHEBI:167630

Term Name:	JTE-607 free base		Search Ontology:
Synonyms:	ethyl (2S)-2-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzamido}-3-phenylpropanoate ethyl N-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl}-L-phenylalaninate JTE-607 (free base) N-[3,5-dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester
Definition:	A secondary carboxamide resulting from the formal condensation of the carboxy group of 3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoic acid with the amino group of ethyl L-phenylalaninate. It inhibits cytokine production in human peripheral blood mononuclear cells (PBMC's) without causing immunosuppression.
References:	CAS:188791-71-1 Chemspider:8114170 PMID:10493164 PMID:15044056 PMID:15280441
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	aromatic ether benzamides dichlorobenzene ethyl ester L-phenylalanine derivative ... Show All 8 Terms aromatic ether benzamides dichlorobenzene ethyl ester L-phenylalanine derivative N-methylpiperazine phenols secondary carboxamide Show first 5 Terms
has_role:	anti-inflammatory agent antineoplastic agent apoptosis inducer CPSF3 inhibitor prodrug anti-inflammatory agent antineoplastic agent apoptosis inducer CPSF3 inhibitor prodrug Show first 5 Terms
inverse is_conjugate_acid_of:	JTE-607(2+) JTE-607(2+) Show first 5 Terms
inverse is_tautomer_of:	JTE-607 zwitterion JTE-607 zwitterion Show first 5 Terms
is_conjugate_base_of:	JTE-607(2+) JTE-607(2+) Show first 5 Terms
is_tautomer_of:	JTE-607 zwitterion JTE-607 zwitterion Show first 5 Terms

PHENOTYPE No data available