Term Name: CD19 molecule
Synonyms: B-lymphocyte surface antigen B4, CD19, differentiation antigen CD19, T-cell surface antigen Leu-12
Definition: A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction.
Ontology: Cell Ontology [PR:000001002]

Relationships
is a type of: protein
inverse has_low_plasma_membrane_amount: late pro-B cell long lived plasma cell
inverse has_plasma_membrane_part: Fraction B/C precursor B cell Fraction D precursor B cell Fraction E immature B cell lymphocyte of B lineage
inverse lacks_plasma_membrane_part: basophil progenitor cell CD14-positive monocyte classical monocyte common dendritic progenitor dendritic cell early pro-B cell eosinophil progenitor cell erythroblast erythroid progenitor cell, mammalian granulocyte group 2 innate lymphoid cell, mouse hematopoietic multipotent progenitor cell hematopoietic oligopotent progenitor cell, lineage-negative hematopoietic stem cell innate lymphoid cell intermediate monocyte mast cell progenitor megakaryocyte progenitor cell natural helper lymphocyte natural killer cell non-classical monocyte pre-conventional dendritic cell proerythroblast reticulocyte