Term Name: platelet-derived growth factor complex
Synonyms: PDGF complex, PDGF-AA dimer, PDGF-AB dimer, PDGF-BB dimer, PDGF-CC dimer, PDGF-DD dimer
Definition: A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).
Ontology: GO: Cellular Component [GO:1990265]    QuickGO    AmiGO

Relationships
is a type of: growth factor complex
inverse has_part: platelet-derived growth factor receptor-ligand complex