Term Name: negative regulation of pyruvate decarboxylation to acetyl-CoA
Synonyms: negative regulation of acetyl-CoA biosynthetic process from pyruvate
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.
Ontology: GO: Biological Process [GO:0160218]    QuickGO    AmiGO

Relationships
is a type of: biological regulation negative regulation of amide metabolic process negative regulation of biosynthetic process negative regulation of nucleobase-containing compound metabolic process negative regulation of phosphate metabolic process negative regulation of small molecule metabolic process negative regulation of sulfur metabolic process regulation of pyruvate decarboxylation to acetyl-CoA
negatively regulates: pyruvate decarboxylation to acetyl-CoA