| Term Name: | gene silencing by piRNA-directed DNA methylation |
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| Synonyms: | |
| Definition: | A small RNA-based gene silencing process in which Piwi-associated RNAs (piRNAs) guide de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. |
| Ontology: | GO: Biological Process [GO:0141176] QuickGO AmiGO |