Term Name: chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway
Synonyms: epigenetic 5-methylcytosine DNA demethylation, oxidative deamination pathway, epigenetic DNA demethylation, oxidative deamination pathway
Definition: An epigenetic cytosine DNA demethylation pathway that includes a deamination step to produce either a thymine (T), or a 5-hydroxymethyluracil (5hmU), if the 5meC had first been converted to 5hmC. A DNA glycosylase (e. g. TDG) recognizes the T mispaired with a G or the 5hmC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair.
Ontology: GO: Biological Process [GO:0141168]    QuickGO    AmiGO

Relationships
is a type of: chromosomal 5-methylcytosine DNA demethylation pathway DNA repair