Term Name: transforming growth factor beta complex
Synonyms: TGF-beta complex, TGF-beta dimer, TGFB complex, TGFB dimer, TGFbeta complex, TGFbeta dimer
Definition: A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP.
Ontology: GO: Cellular Component [GO:0099126]    QuickGO    AmiGO

Relationships
is part of: extracellular matrix
is a type of: protein-containing complex