| Term Name: | isotype switching to IgG isotypes |
|---|---|
| Synonyms: | class switching to IgG isotypes, isotype switch recombination to IgG isotypes |
| Definition: | The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus. |
| Ontology: | GO: Biological Process [GO:0048291] QuickGO AmiGO |