Term Name: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Synonyms: DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
Ontology: GO: Biological Process [GO:0042771]    QuickGO    AmiGO

Relationships
is a type of: intrinsic apoptotic signaling pathway by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage
negatively regulated by: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positively regulated by: positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulated by: regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator