Term Name: negative regulation of insulin receptor signaling pathway by insulin receptor internalization
Synonyms: agonist-stimulated insulin receptor internalization, negative regulation of insulin receptor signalling pathway by insulin receptor internalization
Definition: Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation.
Ontology: GO: Biological Process [GO:0038014]    QuickGO    AmiGO

Relationships
is a type of: insulin receptor internalization negative regulation of insulin receptor signaling pathway negative regulation of signal transduction by receptor internalization
negatively regulates: insulin receptor signaling pathway