Term Name:	Notch receptor processing, ligand-independent
Synonyms:	Notch S1 cleavage
Definition:	The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.
Ontology:	GO: Biological Process [GO:0035334]    QuickGO    AmiGO