Term Name: core-binding factor complex
Synonyms: AML1 complex, CBF complex, PEPB2 complex
Definition: A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.
Ontology: GO: Cellular Component [GO:0016513]    QuickGO    AmiGO

Relationships
is a type of: RNA polymerase II transcription regulator complex