Term Name: negative regulation of signal transduction
Synonyms: down regulation of signal transduction, down-regulation of signal transduction, downregulation of signal transduction, inhibition of signal transduction, negative regulation of signaling pathway, negative regulation of signalling pathway
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
Ontology: GO: Biological Process [GO:0009968]    QuickGO    AmiGO

Relationships
is a type of: biological regulation negative regulation of cell communication negative regulation of response to stimulus negative regulation of signaling regulation of signal transduction
has subtype: extracellular negative regulation of signal transduction negative adaptation of signaling pathway negative regulation of abscisic acid-activated signaling pathway negative regulation of antigen receptor-mediated signaling pathway negative regulation of apolipoprotein A-I-mediated signaling pathway negative regulation of apoptotic signaling pathway negative regulation of auxin mediated signaling pathway negative regulation of brain-derived neurotrophic factor receptor signaling pathway negative regulation of brassinosteroid mediated signaling pathway negative regulation of CD40 signaling pathway negative regulation of corticotropin-releasing hormone receptor activity negative regulation of cytokine activity negative regulation of cytokine-mediated signaling pathway negative regulation of cytokinin-activated signaling pathway negative regulation of ephrin receptor signaling pathway negative regulation of ERBB signaling pathway negative regulation of Fas signaling pathway negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of G protein-coupled receptor signaling pathway negative regulation of GDF15-GFRAL signaling pathway negative regulation of gibberellic acid mediated signaling pathway negative regulation of glucose mediated signaling pathway negative regulation of glutamate receptor signaling pathway negative regulation of growth hormone receptor signaling pathway negative regulation of hepatocyte growth factor receptor signaling pathway negative regulation of insulin receptor signaling pathway negative regulation of insulin-like growth factor receptor signaling pathway negative regulation of integrin-mediated signaling pathway negative regulation of intracellular signal transduction negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation of netrin-activated signaling pathway negative regulation of neuronal signal transduction negative regulation of neurotrophin TRK receptor signaling pathway negative regulation of Notch signaling pathway negative regulation of peptidoglycan recognition protein signaling pathway negative regulation of platelet-derived growth factor receptor signaling pathway negative regulation of receptor guanylyl cyclase signaling pathway negative regulation of receptor signaling pathway via STAT negative regulation of red or far-red light signaling pathway negative regulation of Roundabout signaling pathway negative regulation of semaphorin-plexin signaling pathway negative regulation of sevenless signaling pathway negative regulation of signal transduction by receptor internalization negative regulation of signal transduction in absence of ligand negative regulation of smoothened signaling pathway negative regulation of sphingolipid mediated signaling pathway negative regulation of Toll signaling pathway negative regulation of toll-like receptor 1 signaling pathway negative regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 4 signaling pathway negative regulation of toll-like receptor 5 signaling pathway negative regulation of toll-like receptor 6 signaling pathway negative regulation of toll-like receptor 10 signaling pathway negative regulation of toll-like receptor 15 signaling pathway negative regulation of toll-like receptor signaling pathway negative regulation of torso signaling pathway negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway negative regulation of vascular endothelial growth factor receptor signaling pathway negative regulation of vascular endothelial growth factor signaling pathway negative regulation of Wnt signaling pathway termination of signal transduction
negatively regulates: signal transduction