Term Name: sterol 12-alpha-hydroxylase activity
Synonyms: cytochrome P450 CYP8B1
Definition: Catalysis of the reaction: a steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 12-alpha-hydroxysteroid + oxidized [NADPH--hemoprotein reductase]- H2O +H+.
Ontology: GO: Molecular Function [GO:0008397]    QuickGO    AmiGO

Relationships
is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen steroid hydroxylase activity