Term Name:	phospholipase C-activating G protein-coupled receptor signaling pathway
Synonyms:	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger, G protein signaling, coupled to IP3 second messenger (phospholipase C activating), G protein signalling, coupled to IP3 second messenger (phospholipase C activating), G-protein coupled receptor signaling pathway coupled to IP3 second messenger, G-protein signaling, coupled to IP3 second messenger (phospholipase C activating), G-protein signalling, coupled to IP3 second messenger (phospholipase C activating), phospholipase C-activating G-protein coupled receptor signaling pathway, PLC-activating GPCR signaling pathway, protein kinase C-activating G protein-coupled receptor signaling pathway
Definition:	A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). IP3 regulates the opening of calcium channels in intracellular calcium store, leading to the release of calcium into the cytosol. Calcium and DAG activate protein kinase C (PKC), which in turn activates downstream effectors.
Ontology:	GO: Biological Process [GO:0007200]    QuickGO    AmiGO