Term Name: | activation-induced cell death of T cells |
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Synonyms: | activated T cell apoptosis, activation-induced cell death of T lymphocytes, activation-induced cell death of T-cells, activation-induced cell death of T-lymphocytes, AICD, antigen-driven apoptosis |
Definition: | A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. |
Ontology: | GO: Biological Process [GO:0006924] QuickGO AmiGO |