Term Name: anaphase-promoting complex
Synonyms: anaphase promoting complex, APC, cyclosome
Definition: A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
Ontology: GO: Cellular Component [GO:0005680]    QuickGO    AmiGO

Relationships
is a type of: cullin-RING ubiquitin ligase complex nuclear ubiquitin ligase complex