Term Name:	metalloendopeptidase activity
Synonyms:	metalloendoprotease activity, metalloendoproteinase activity
Definition:	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Ontology:	GO: Molecular Function [GO:0004222]    QuickGO    AmiGO