| Term Name: | granuloma formation |
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| Synonyms: | |
| Definition: | The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic. |
| Ontology: | GO: Biological Process [GO:0002432] QuickGO AmiGO |