Term Name:	tetanus
Synonyms:	clostridial tetanus, Infection due to Clostridium tetani
Definition:	A primary bacterial infectious disease that results in prolonged contraction of skeletal muscle fibers, has_material_basis_in Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord, where it binds irreversibly to receptors inhibiting neurotransmission. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli.
Ontology:	Human Disease [DOID:11338]   ( DOID:11338 )