Term Name:	hereditary spastic paraplegia 85
Synonyms:	spastic paraplegia 85 autosomal recessive, SPG85
Definition:	A hereditary spastic paraplegia characterized by onset of motor symptoms (e.g. spasticity and hyperreflexia of the lower limbs) in the first few years of life that has_material_basis_in homozygous or compound heterozygous mutation in the RNF170 gene on chromosome 8p11.21.
Ontology:	Human Disease [DOID:0112345]   ( DOID:0112345 )