Term Name:	immunodeficiency 56
Synonyms:	combined immunodeficiency due to IL21R deficiency, IL21R immunodeficiency, IMD56
Definition:	A combined T cell and B cell immunodeficiency characterized by B- and T-cell defects including defective class-switched B cells, low IgG, defective antibody response, and defective T-cell responses to certain antigens, and variable dysfunction of NK cells that has_material_basis_in homozygous or compound heterozygous mutation in the IL21R gene on chromosome 16p12.1.
Ontology:	Human Disease [DOID:0111982]   ( DOID:0111982 )