Term Name:	high molecular weight kininogen deficiency
Synonyms:	congenital high-molecular-weight kininogen deficiency, Fitzgerald trait, HMWK deficiency
Definition:	A blood coagulation disease characterized by deficiency of high molecular weight kininogen but not of low molecular weight kininogen resulting in abnormal surface-mediated activation of fibrinolysis that has_material_basis_in homozygous or compound heterozygous mutation in the KNG1 gene on chromosome 3q27.3. Both high and low molecular weight kininogen are encoded by the KNG1 gene.
Ontology:	Human Disease [DOID:0111676]   ( DOID:0111676 )