Term Name:	IGSF1 deficiency syndrome
Synonyms:	central hypothyroidism and testicular enlargement, CHTE, X-linked central congenital hypothyroidism with late-onset macroorchidism, X-linked central congenital hypothyroidism with late-onset testicular enlargement
Definition:	A syndrome characterized by hypothyroidism that is present at birth, delayed testosterone increase in puberty, and testicular enlargement in adulthood that has_material_basis_in mutation of the IGSF1 gene on chromosome Xq26.
Ontology:	Human Disease [DOID:0111140]   ( DOID:0111140 )