Term Name: aromatase excess syndrome
Synonyms: AEXS, familial hyperestrogenism, hereditary prepubertal gynecomastia, increased aromatase activity
Definition: A reproductive system disease characterized by increased extraglandular aromatization of steroids resulting in heterosexual precocity in males and isosexual precocity in females, and has_material_basis_in autosomal dominant inheritance of fusion of the aromatase gene (CYP19A1) with various partners, brought about by translocations and resulting in gain of function of the CYP19A1 gene.
Ontology: Human Disease [DOID:0090122]   ( DOID:0090122 )

Relationships
is a type of: reproductive system disease