Term Name:	lymphoproliferative syndrome 1
Synonyms:	LPFS1
Definition:	A lymphoproliferative syndrome characterized by autosomal recessive inheritance, early childhood onset of Epstein-Barr virus-associated immune dysregulation typically manifesting as lymphoma, lymphomatoid granulomatosis, hemophagocytic lymphohistiocytosis, Hodgkin disease, and-or hypogammaglobulinemia and that has_material_basis_in homozygous mutation in the ITK gene on chromosome 5q32.
Ontology:	Human Disease [DOID:0060707]   ( DOID:0060707 )