Term Name: | GRN-related frontotemporal lobar degeneration with Tdp43 inclusions |
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Synonyms: | frontotemporal dementia 2 |
Definition: | A frontotemporal dementia characterized by variable phenotypic expression typically including social, behavioral, or language deterioration, rather than memory or motor deficits and the presence of TARDBP-positive inclusions that has_material_basis_in mutation in the GRN gene on chromosome 17q21.31. |
Ontology: | Human Disease [DOID:0060672] ( DOID:0060672 ) |