| Term Name: | obsolete interleukin-7 receptor alpha deficiency |
|---|---|
| Synonyms: | IL-7R |
| Definition: | A severe combined immunodeficiency that results from defective IL7R expression causes T-B+NK+ SCID. Loss of IL-7R function leads to the loss of an antiapoptotic signal, resulting in a loss of T-cell selection in thymus. |
| Ontology: | Human Disease [DOID:0060015] ( DOID:0060015 ) |
| Obsolete | true |