Term Name:	MHC class I deficiency
Synonyms:	bare lymphocyte syndrome type I, BLS, TYPE I, BLSI, HLA CLASS I DEFICIENCY
Definition:	A severe combined immunodeficiency that is characterized by recurrent bacterial, viral, and fungal infections, especially of the lung, and sterile necrotizing granulomas of the skin, develops_from deficiency or decreased surface expression of MHC Class I, has_material_basis_in autosomal recessive inheritance of mutation affecting MHC Class I production or expression and frequently involves TAP1 and TAP2 subunits, and is typically asymptomatic in infancy.
Ontology:	Human Disease [DOID:0060009]   ( DOID:0060009 )