Term Name: Fraction D precursor B cell
Synonyms: Fr. D, Fraction D pre-B cell
Definition: A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive.
Ontology: Cell Ontology [CL:0002052]

Relationships
develops from: Fraction C' precursor B cell
develops into: Fraction E immature B cell
is a type of: Fraction B/C precursor B cell precursor B cell
has_low_plasma_membrane_amount: leukosialin
has_not_completed: immunoglobulin light chain V-J recombination
has_plasma_membrane_part: CD19 molecule complement component C1q receptor glutamyl aminopeptidase interleukin-2 receptor subunit alpha receptor-type tyrosine-protein phosphatase C isoform CD45R signal transducer CD24
lacks_plasma_membrane_part: pre-B cell receptor complex