Term Name: T follicular helper cell
Synonyms: follicular B helper T cell, follicular helper T cell, follicular helper T-cell, follicular T cell, follicular T-cell, follicular T-helper cell, T(FH), Tfh
Definition: A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that expresses is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production.
Ontology: Cell Ontology [CL:0002038]

Relationships
develops from: activated CD4-positive, alpha-beta T cell
is a type of: CD4-positive helper T cell
capable_of: positive regulation of isotype switching
has_part: B-cell lymphoma 6 protein
has_plasma_membrane_part: C-X-C chemokine receptor type 5 inducible T-cell costimulator programmed cell death protein 1
lacks_plasma_membrane_part: C-C chemokine receptor type 7