Term Name: splenic red pulp macrophage
Synonyms:
Definition: A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low.
Ontology: Cell Ontology [CL:0000874]

Relationships
is part of: red pulp of spleen
is a type of: splenic macrophage
capable_of: erythrocyte clearance immune response
has_low_plasma_membrane_amount: integrin alpha-M sialoadhesin
has_plasma_membrane_part: C-type lectin domain family 6 member A EGF-like module-containing mucin-like hormone receptor-like 1 macrophage mannose receptor 1 macrosialin
lacks_plasma_membrane_part: integrin alpha-X