Term Name: | LFM-A13 |
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Synonyms: | (2Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide, (2Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide, 2Z-cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide, alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide, DDE-28 |
Definition: | An enamide obtained by formal condensation of the carboxy group of (2Z)-2-cyano-3-hydroxybut-2-enoic acid with the amino group of 2,5-dibromoaniline. It is a dual-function inhibitor of Bruton's tyrosine kinase (BTK) and Polo-like kinases (PLK) that exhibits anticancer properties. |
Ontology: | ChEBI [CHEBI:183517] ( EBI ) |