Term Name: pimasertib
Synonyms: AS 703026, AS-703026, AS703026, MSC 1936369B, MSC-1236369B, MSC1936369B, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)-4-pyridinecarboxamide, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, pimasertib, pimasertibum, SAR 245509, SAR-245509, SAR245509
Definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(2-fluoro-4-iodoanilino)pyridine-4-carboxylic acid with the amino group of (2S)-3-aminopropane-1,2-diol. It is a potent inhibitor of the mitogen-activated protein kinases MEK1 and MEK2 with potential antineoplastic activity.
Ontology: ChEBI [CHEBI:94793]  ( EBI )

Relationships
is a type of: aminopyridine difluorobenzene diol primary alcohol pyridinecarboxamide secondary alcohol secondary carboxamide substituted aniline
has_role: antineoplastic agent apoptosis inducer EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor