Term Name: CHIR-265
Synonyms: 1-methyl-5-({2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy)-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine, CHIR 265, CHIR265, RAF 265, RAF-265, RAF265
Definition: A member of the class of benzimidazoles that is 1H-benzimidazole substituted by methyl, [4-(trifluoromethyl)phenyl]amino, and {2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy groups at positions 1, 2, and 5, respectively. It is an inhibitor of RAF kinases, including the BRAF V600E mutant.
Ontology: ChEBI [CHEBI:91451]  ( EBI )

Relationships
is a type of: (trifluoromethyl)benzenes aromatic ether benzimidazoles imidazoles organofluorine compound pyridines substituted aniline
has_role: angiogenesis inhibitor antineoplastic agent antiviral agent apoptosis inducer B-Raf inhibitor EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor