Term Name: (E)-3-tosylacrylonitrile
Synonyms: (2E)-3-[(4-methylphenyl)sulfonyl]acrylonitrile, (3E)3-(p-toluenesulfonyl)acrylonitrile, (E)-3-(4-methylphenylsulfonyl)-2-propenenenitrile, (E)-3-(p-toluenesulfonyl)acrylonitrile, BAY-11-7082, BAY-11-7821, Bay-117082, BAY-117821, beta-(cyanovinyl)-p-tolylsulfone
Definition: A nitrile that is acrylonitrile in which the hydrogen located beta,trans to the cyano group is replaced by a tosyl group. It is an inhibitor of cytokine-induced IkappaB-alpha phosphorylation in cells.
Ontology: ChEBI [CHEBI:85928]  ( EBI )

Relationships
is a type of: nitrile sulfone
has_role: apoptosis inducer EC 2.7.11.10 (IkappaB kinase) inhibitor EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor non-steroidal anti-inflammatory drug platelet aggregation inhibitor