Term Name: ACT-132577
Synonyms: N-[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl]sulfuric diamide
Definition: A member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension.
Ontology: ChEBI [CHEBI:76609]  ( EBI )

Relationships
is a type of: aromatic ether organobromine compound pyrimidines sulfamides
has_functional_parent: ethylene glycol
has_role: antihypertensive agent drug metabolite endothelin receptor antagonist xenobiotic metabolite
inverse has_functional_parent: macitentan