Term Name: naproxcinod
Synonyms: (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester, 4-(nitrooxy)butyl (2S)-2-(6-methoxy-2-naphthyl)propanoate, AZD 3582, AZD3582, HCT 3012, naproxcinod, naproxcinodum, Naproxen-N-butyl nitrate, Nitronaproxen
Definition: A carboxylic ester obtained by formal condensation of the carboxy group of naproxen with the hydroxy group of 4-(nitrooxy)butanol. A cyclooxygenase-inhibiting nitric oxide donator that is metabolised to naproxen and a nitric oxide donating moiety, effective in treatment of osteoarthritis.
Ontology: ChEBI [CHEBI:76254]  ( EBI )

Relationships
is a type of: carboxylic ester methoxynaphthalene nitrate ester
has_functional_parent: butane-1,4-diol naproxen
has_role: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor nitric oxide donor non-narcotic analgesic non-steroidal anti-inflammatory drug prodrug