Term Name: trametinib
Synonyms: GSK 1120212, JTP 74057, N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide, trametinib, trametinibum
Definition: A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment.
Ontology: ChEBI [CHEBI:75998]  ( EBI )

Relationships
is a type of: acetamides aromatic amine cyclopropanes organofluorine compound organoiodine compound pyridopyrimidine ring assembly
has_role: anticoronaviral agent antineoplastic agent EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor geroprotector
inverse has_part: trametinib dimethyl sulfoxide