Term Name: rilpivirine
Synonyms: 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, rilpivirine, TMC 278, TMC278
Definition: An aminopyrimidine that is pyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 4-cyanophenyl and 4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl groups respectively. Used for treatment of HIV.
Ontology: ChEBI [CHEBI:68606]  ( EBI )

Relationships
is a type of: aminopyrimidine nitrile
has_role: EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor HIV-1 reverse transcriptase inhibitor
inverse is_conjugate_acid_of: rilpivirine(1+)
is_conjugate_base_of: rilpivirine(1+)