Term Name: ageladine A
Synonyms: 4-(4,5-dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridin-2-amine
Definition: An imidazopyridine that is 1H-imidazo[4,5-c]pyridin-2-amine substituted by a 4,5-dibromo-1H-pyrrol-2-yl group at position 4. It is an alkaloid isolated from a marine sponge Agelas nakamurai and acts as an inhibitor of the matrix metalloproteinases, the key enzymes involved in tumour growth, migration, angiogenesis, invasion and metastasis.
Ontology: ChEBI [CHEBI:65373]  ( EBI )

Relationships
is a type of: alkaloid aromatic amine imidazopyridine organobromine compound pyrroles
has_role: angiogenesis inhibitor antineoplastic agent matrix metalloproteinase inhibitor metabolite