Term Name: sulindac sulfone
Synonyms: 5-Fluoro-2-methyl-1-((Z)-p-(methylsulfonyl)benzylidene)indene-3-acetic acid, cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid, exisulind, {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl}acetic acid
Definition: A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor.
Ontology: ChEBI [CHEBI:64212]  ( EBI )

Relationships
is a type of: monocarboxylic acid organofluorine compound sulfone
has_functional_parent: sulindac
has_role: apoptosis inducer cyclooxygenase 2 inhibitor EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor