Term Name: leflunomide
Synonyms: 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide, 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide, alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide, Arava, leflunomida, leflunomide, leflunomidum
Definition: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-methyl-1,2-oxazole-4-carboxylic acid with the anilino group of 4-(trifluoromethyl)aniline. The prodrug of teriflunomide.
Ontology: ChEBI [CHEBI:6402]  ( EBI )

Relationships
is a type of: (trifluoromethyl)benzenes isoxazoles monocarboxylic acid amide
has_role: antineoplastic agent antiparasitic agent EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor hepatotoxic agent immunosuppressive agent non-steroidal anti-inflammatory drug prodrug pyrimidine synthesis inhibitor tyrosine kinase inhibitor