Term Name: tenofovir (anhydrous)
Synonyms: (R)-PMPA, ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonic acid, anh. tenofovir, anhydrous tenofovir, tenofovir, tenofovir (anh.)
Definition: A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
Ontology: ChEBI [CHEBI:63625]  ( EBI )

Relationships
is a type of: nucleoside analogue phosphonic acids
has_role: antiviral drug drug metabolite HIV-1 reverse transcriptase inhibitor
inverse has_functional_parent: tenofovir disoproxil
inverse has_part: tenofovir hydrate
inverse is_conjugate_base_of: tenofovir(1-)
is_conjugate_acid_of: tenofovir(1-)