Term Name: fluprostenol
Synonyms: EINECS 255-029-3, fluprostenol, fluprostenolum, ICI 81,008, rac-(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoic acid, travoprost acid, travoprost free acid
Definition: An organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea.
Ontology: ChEBI [CHEBI:60782]  ( EBI )

Relationships
is a type of: (trifluoromethyl)benzenes hydroxy monocarboxylic acid prostaglandins Falpha
has_role: abortifacient antiglaucoma drug antihypertensive agent female contraceptive drug prostaglandin receptor agonist
inverse has_functional_parent: travoprost